Tag

Antibiotic Development

All articles tagged with #antibiotic development

health2 years ago•8 min saved

"Breakthrough Synthetic Molecule Defeats Drug-Resistant Bacteria"

Researchers at UC Santa Barbara have developed a new class of antibiotics, called conjugated oligoelectrolytes (COEs), which have shown promise in overcoming drug-resistant bacteria. These COEs have demonstrated effectiveness against a broad array of bacterial infections and have the potential to evade antibiotic resistance. The compounds target bacterial membranes, inhibiting essential functions and disrupting biofilm formation. The research team is working on further refining the molecules for potential clinical trials, with support from various institutes and research collaborations globally.

via Phys.org|

#antibiotic-development #antibiotics #bacteria

health2 years ago•3 min saved

"Synthetic Molecule: A Potent Antibiotic Against Drug-Resistant Superbugs"

Harvard researchers have developed a new synthetic antibiotic, cresomycin, which effectively kills drug-resistant bacteria, including Staphylococcus aureus and Pseudomonas aeruginosa. The compound demonstrates improved binding to bacterial ribosomes, overcoming resistance mechanisms. Supported by a $1.2 million grant from CARB-X, the team aims to advance cresomycin through preclinical studies. The fully synthetic molecule draws inspiration from lincosamides and utilizes a component-based synthesis approach, showing promise in the fight against superbugs and addressing the global public health crisis of antimicrobial resistance.

via EurekAlert|

#antibiotic-development #antibiotics #bacterial-infections

health-medicine2 years ago•3 min saved

"Breakthrough Antibiotic Kills Drug-Resistant Superbugs in Trials"

Researchers have discovered a new class of antibiotic, zosurabalpin, which effectively kills the deadly drug-resistant superbug, carbapenem-resistant Acinetobacter baumannii (Crab). Zosurabalpin works by blocking a molecular machine that transports a toxin used by Crab, causing the bacteria to die. While the antibiotic is currently in phase 1 clinical trials, it shows promise in combating antibiotic-resistant infections and reducing the emergence of resistance.

via ScienceAlert|

#antibiotic-development #antibiotics #drug-resistance

science-and-health2 years ago•3 min saved

The Powerful Anti-Microbial Properties of Australian Honeypot Ant Honey

A study conducted by the University of Sydney has found that honey produced by Australian honeypot ants possesses unique antimicrobial properties against bacteria and fungi. This discovery validates the traditional medicinal use of ant honey by Indigenous communities. The researchers identified that the ant honey has a distinct mechanism of action compared to Manuka honey and could potentially be used as a starting point for developing new antibiotics. The ant honey was found to be effective against Staphylococcus aureus bacteria and two species of fungi. This research highlights the potential of ant honey in the field of medicine and antibiotic development.

via SciTechDaily|

#antibiotic-development #antimicrobial-properties #australian-honeypot-ant