Blood Test Signals Alzheimer's Onset Years Before Symptoms
TL;DR Summary
A blood biomarker, p-tau217, tracks brain Alzheimer’s pathology and, in a study of 603 older adults, could estimate how many years remain before symptoms appear. This could enable earlier diagnosis and shorter, cheaper preventive trials, though it isn’t yet recommended for general asymptomatic screening. The researchers hint at improving accuracy by combining p-tau217 with other biomarkers and note a web tool and GitHub code for broader exploration.
- Blood Tests Could Provide Early Warning Of Alzheimers Disease Hackaday
- Blood test predicts dementia in women as many as 25 years before symptoms begin Medical Xpress
- Scientists Find Alzheimer’s Clues Hidden in the Shape of Blood Proteins SciTechDaily
- Head-to-head comparison of brain-derived pTau217 and total pTau217 for brain amyloid and tau pathology classification PNAS
- Scientists pinpoint protein shapes that track Alzheimer’s progression EurekAlert!
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