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Protein Research

All articles tagged with #protein research

science-and-health1 year ago•3 min saved

Protein Discovery Promises Healthier Aging

Researchers at McMaster University have discovered that the protein MANF aids in cellular cleanup by managing toxic protein clumps, which could lead to new treatments for age-related diseases like Alzheimer's and Parkinson's. The study, published in the Proceedings of the National Academy of Sciences, highlights MANF's role in maintaining cellular homeostasis and suggests its potential as a therapeutic target to promote healthier aging by enhancing the natural cellular clean-up system.

via SciTechDaily|

#aging #cellular-health #longevity

science1 year ago•5 min saved

Genetic Insights: Unraveling Autism's Molecular Mysteries

An international team of scientists has identified a 24-letter DNA sequence linked to autism, which may explain cases where no significant genetic mutation is detected. The sequence is part of the CPEB4 protein, crucial for brain development, and its absence deregulates 200 genes associated with autism. Researchers aim to test if adding the missing amino acids can reverse autism symptoms, with preliminary lab results showing promise. This discovery could lead to new therapeutic approaches for autism spectrum disorders.

via EL PAÍS USA|

#autism #brain-development #genetics

science-and-technology2 years ago•3 min saved

Unveiling the Enigmatic 'Unknome': Exploring the Secrets of Human Genes and Proteins

Researchers from the UK have created a publicly available database called the "unknome," which compiles information on thousands of understudied proteins encoded by genes in the human genome. The database assigns a "knownness" score to each protein based on factors such as function, conservation, and subcellular compartmentalization. By prioritizing research on proteins with low knownness scores, the database aims to accelerate the understanding of these genes and their potential roles in critical cellular processes. The authors tested the database by studying genes in humans and flies, revealing that many of these understudied proteins contribute to essential functions. The unknome database provides a platform for identifying and selecting important genes of unknown function, bridging the gap in biological knowledge.

via Phys.org|

#biological-knowledge #database #human-genes