Tag

Propofol

All articles tagged with #propofol

Brainwave marker pinpoints moment consciousness fades under anesthesia
science1 month ago

Brainwave marker pinpoints moment consciousness fades under anesthesia

A study with 31 participants under propofol anesthesia identifies a distinctive brain-wave pattern and decreasing inter-regional connectivity—especially between the parietal cortex and thalamus and between parietal and occipital areas—that mark loss of consciousness, suggesting an actionable biomarker to refine dosing, though findings are limited to one anesthetic and rely on new methods to infer whole-brain signals from scalp data.

"Anesthesia Induces Unconsciousness by Disrupting Brain Activity, Study Finds"
sciencehealth1 year ago

"Anesthesia Induces Unconsciousness by Disrupting Brain Activity, Study Finds"

MIT researchers have discovered that the common sedative propofol disrupts the brain's ability to control highly excitable neurons, leading to a loss of consciousness. By studying brain activity in rhesus macaque monkeys, they found that propofol inhibits inhibitory neurons, causing escalating instability in brain activity. This new theory adds to the complex understanding of how anesthetics work, with potential implications for improving the safety of various anesthetic drugs.

"How Anesthesia Induces Unconsciousness by Disrupting Brain Activity"
science1 year ago

"How Anesthesia Induces Unconsciousness by Disrupting Brain Activity"

MIT neuroscientists have discovered that the anesthesia drug propofol induces unconsciousness by disrupting the brain's balance between stability and excitability, leading to escalating instability. This finding, achieved through a novel technique for analyzing neuron activity, could help develop better tools for monitoring anesthesia and potentially apply to other brain states and neuropsychiatric disorders.

"How Anesthesia Drugs Induce Unconsciousness Unveiled"
science-and-health1 year ago

"How Anesthesia Drugs Induce Unconsciousness Unveiled"

MIT neuroscientists have discovered that the anesthesia drug propofol induces unconsciousness by disrupting the brain's balance between stability and excitability, leading to escalating instability. This finding, published in Neuron, could help develop better tools for monitoring anesthesia and may apply to other anesthetic drugs and neuropsychiatric conditions.

Miami Nurse Collapses in Restroom with Surgical Drug IV - What Happened Next Will Shock You
healthcare2 years ago

Miami Nurse Collapses in Restroom with Surgical Drug IV - What Happened Next Will Shock You

A Miami nurse at HCA Florida Mercy Hospital, Groennou Nieves, has been suspended by the state Board of Nursing after being found unconscious in a restroom with a missing surgical drug, propofol, in her IV line. She will need to undergo evaluation and follow treatment recommendations for substance abuse before potentially returning to work in 2025. Nieves tested positive for cocaine in a drug test, and her state license suspension will continue until she is cleared by an evaluator.