Tag

Probes

All articles tagged with #probes

science4 months ago

New Imaging Techniques Uncover How Dual Agonist Drugs Target Brain and Pancreas for Diabetes and Obesity

The article discusses the development of fluorescent probes, daLUXendin544 and daLUXendin660, which specifically target GLP1R and GIPR receptors in the pancreas and brain, enabling detailed visualization of cell targets and receptor nanodomains, and providing insights into the cellular mechanisms of dual agonists like tirzepatide for diabetes and obesity treatment.

finance2 years ago

"Morgan Stanley Settles US Block Trading Probes for $249 Million"

Morgan Stanley has agreed to pay $249 million to settle probes by US authorities into its alleged deceptive practices in the handling of certain trades, known as "block trades." The settlement resolves investigations by the Securities and Exchange Commission and the Department of Justice, which accused the bank of misleading clients about the way it executed their trades.