Tag

Organoid Model

All articles tagged with #organoid model

science7 months ago•5 min saved

Stem Cells Could Restore Sense of Smell

Researchers at Tufts University developed a simple 3D mouse organoid model to study how dormant stem cells, specifically horizontal basal cells (HBCs), support the regeneration of olfactory neurons. Their findings suggest that these cells play a crucial role in repairing smell loss, which can be impaired by aging or viral infections like COVID-19. The model aims to facilitate drug testing and eventually lead to human organoids for treating smell disorders.

via Neuroscience News|

#aging #covid-19 #olfactory-regeneration

neuroscience1 year ago•7 min saved

"Creation of Early Human Central Nervous System Model Using Stem Cells"

Researchers have developed a groundbreaking 3D human organoid system that accurately models the early stages of the human central nervous system (CNS) using patient-derived stem cells, offering new possibilities for studying human brain development and diseases. This comprehensive model simulates the development of the brain and spinal cord, potentially leading to personalized treatment strategies for neurological and neuropsychiatric disorders. The innovation provides a unique platform for understanding the intricacies of the human CNS and its disorders, surpassing the capabilities of previous models.

via Neuroscience News|

#central-nervous-system #human-brain-development #neurological-disorders

neuroscience2 years ago•5 min saved

Unveiling the Mysteries of the Dopaminergic System: Insights from Organoid and Assembloid Models

Researchers have developed an organoid model that replicates the structure, connectivity, and functionality of the human dopaminergic system, shedding light on Parkinson's disease and the long-term effects of chronic cocaine use. The model shows promise in improving cell therapies for Parkinson's disease and provides insights into addiction research.

via Neuroscience News|

#addiction #cell-therapies #dopaminergic-system