Tag

Omalizumab

All articles tagged with #omalizumab

"Xolair: A Promising Treatment for Multiple Food Allergies"
health1 year ago

"Xolair: A Promising Treatment for Multiple Food Allergies"

The FDA has approved the use of Xolair, an asthma drug also known as omalizumab, for severe food allergies, offering hope for those affected. Xolair, administered through injections, reduces the likelihood of severe allergic reactions in cases of accidental exposure to allergens, providing a preventative measure for individuals with food allergies. While it represents a significant breakthrough in allergy treatment, questions remain about its long-term effectiveness and accessibility due to its cost.

New Injection Protects Against Severe Food Allergy Reactions
health-medicine1 year ago

New Injection Protects Against Severe Food Allergy Reactions

A study has shown that the asthma drug omalizumab can protect people with severe food allergies, allowing them to ingest small amounts of allergenic foods without severe reactions. The drug, approved by the FDA for food allergies, works by targeting a specific type of human antibody and has been found to be effective in raising tolerance to various allergenic foods. While the drug does not eliminate allergies, it raises the threshold for triggering a reaction. Other potential food allergy treatments being researched include dupilumab and abrocitinib, as well as early allergen exposure in infants.

"Xolair: FDA-Approved Treatment for Severe Food Allergies"
health1 year ago

"Xolair: FDA-Approved Treatment for Severe Food Allergies"

The FDA has approved the antibody drug omalizumab (Xolair) as an injection to reduce allergic reactions to food in people aged 1 and up. In a trial, participants who received omalizumab were more likely to tolerate allergy-inducing foods compared to those who received a placebo. The drug works by binding to immunoglobulin E (IgE) antibodies involved in allergic responses. While it won't eliminate food allergies, it can reduce the health impact of accidental exposure. Side effects include injection site reactions, fever, joint pain, rash, and the possibility of other infections and malignancies.

Breakthrough Antibody Treatment Mitigates Allergic Reactions to Multiple Foods, NIH Trial Reveals
health2 years ago

Breakthrough Antibody Treatment Mitigates Allergic Reactions to Multiple Foods, NIH Trial Reveals

An interim analysis of an advanced clinical trial sponsored by the National Institute of Allergy and Infectious Diseases (NIAID) has shown that a monoclonal antibody treatment called omalizumab significantly increased the amount of multiple common foods that food-allergic children and adolescents could consume without experiencing an allergic reaction. The trial, called OUtMATCH, aims to assess the efficacy of omalizumab in reducing allergic reactions to small amounts of food allergens. The positive results have led to a recommendation to halt enrollment in the first stage of the trial, and the FDA is reviewing a supplemental biologics license application for omalizumab for food allergy based on this interim analysis.