Tag

Muscle Regeneration

All articles tagged with #muscle regeneration

health1 year ago•4 min saved

"Cell-Based Therapy for Rotator Cuff Muscle Repair"

Researchers from Georgia Tech have developed a novel cell-based dual treatment for rotator cuff injuries, aiming to address poor clinical outcomes associated with common rotator cuff surgery. The treatment involves a combination of a bone marrow mobilizing agent and local injection of microparticles loaded with a protein called stromal cell-derived factor (SDF) to attract healing cells to the injury site, resulting in enhanced muscle regeneration. This innovative approach shows promise for improving muscle regeneration and has potential applications beyond the rotator cuff.

via Medical Xpress|

#biomedical-engineering #cell-based-treatment #health

science-and-technology2 years ago•4 min saved

Revolutionary Stem Cell Research Promises Muscle Regeneration

Researchers at UCLA have made progress in developing stem cell therapies for regenerating skeletal muscle in humans. By transplanting lab-grown muscle stem cells into mice, they discovered the importance of the stem cell "niche" in supporting the survival and function of the cells. Removing existing stem cells and optimizing the muscle niche allowed the transplanted cells to persist and repair muscle injuries. The study highlights the need to optimize both the muscle niche and the muscle progenitor cells themselves for successful stem cell therapies in the future.

via Phys.org|

#lab-grown-cells #muscle-regeneration #science-and-technology

science-and-technology2 years ago•6 min saved

"Revolutionary Magnetic Workout Enhances Lab-Grown Muscles for Robots"

Scientists at MIT have developed a magnetic hydrogel "sandwich" that controls the orientation of muscle cells in a lab dish, mimicking the alignment found in natural muscles. By changing the position of magnets, the muscle cells aligned into fibers that contracted in synchrony. This breakthrough could lead to the development of lab-grown tissues for grafting into people with damaged muscles or coating robots with human-like senses and flexible motor control. The system also sheds light on muscle cells' ability to adapt, align, and regenerate.

via Singularity Hub|

#biomanufacturing #lab-grown-muscles #magnetic-hydrogel

health2 years ago•3 min saved

"Stanford Scientists Uncover Anti-Aging Molecule for Muscle and Nerve Regeneration"

Stanford scientists have discovered a molecule that could potentially be developed into an anti-aging drug. By blocking the action of an aging-related protein called 15-PGDH, the researchers were able to repair broken nerve and muscle fiber connections, leading to the restoration of strength and muscle mass in lab mice. This discovery has significant implications for adults experiencing muscle weakness with age and for individuals with muscle-wasting diseases like ALS. The study also revealed that inhibiting 15-PGDH can regenerate damaged motor neurons in the brain and spinal cord, offering potential treatments for various neuromuscular disorders.

via Daily Mail|

#als #anti-aging-drug #health

health2 years ago•3 min saved

Revitalizing Aging Muscles: The Science of Youthful Strength

Scientists at the Instituto de Medicina Molecular João Lobo Antunes in Portugal have discovered a protein called MANF that can regulate the immune system and restore the regenerative capacity of muscles in aging mice. The protein enhances the ability of immune cells known as macrophages to remove residue in the muscle undergoing regeneration. Increasing MANF levels in aged muscle can restore its regenerative capacity, offering a promising avenue for improving the efficacy of current muscle regenerative therapies and combating age-related diseases. The findings could be used to promote the reparative function of the immune system and improve the success of current stem-cell-based therapies for muscle regeneration.

via SciTechDaily|

#aging #health #immune-system