Tag

Molecular Atlas

All articles tagged with #molecular atlas

"AI Links Brain Tissue Patterns to Disease Symptoms"
health-and-medicine1 year ago

"AI Links Brain Tissue Patterns to Disease Symptoms"

A new AI language model has linked clinical symptoms with brain tissue data from over 3,000 donors, offering a novel approach to understanding brain diseases and reducing misdiagnoses. The model identified 90 different symptoms across five domains and aims to create a molecular atlas of brain diseases, potentially leading to the development of targeted therapies and more accurate diagnoses during a patient’s lifetime. This research could significantly improve the understanding of neurodegenerative disorders and help identify associated molecular and cellular features.

New cell types and molecular features discovered in cochlea cell atlas through single-cell sequencing.
science2 years ago

New cell types and molecular features discovered in cochlea cell atlas through single-cell sequencing.

Researchers at the Pasteur Institute in France have created a comprehensive transcriptomic atlas of the mouse cochlea using single-cell sequencing, identifying nearly all cochlear cell types and discovering three previously unknown cell types. The study sheds light on the molecular basis of the tonotopic gradient of the basilar membrane's biophysical characteristics and reveals the expression of deafness genes in several cochlear cell types. The atlas will be useful for finding overlooked cochlear cells affected by particular deficits and may reveal causal sources for deafness of unknown origin.