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Iron Accumulation

All articles tagged with #iron accumulation

health1 year ago

Brain-Friendly Diets: Lower Iron for Better Cognitive Health

A study by the University of Kentucky suggests that diets rich in antioxidants, vitamins, and iron-chelating nutrients, such as the Mediterranean or DASH diets, may reduce brain iron accumulation, which is linked to cognitive decline in aging. Over three years, participants with higher intake of these nutrients showed less brain iron buildup and better cognitive performance, highlighting the potential of dietary interventions to support brain health and combat age-related cognitive decline.

via Neuroscience News|
#antioxidants#brain-health#cognitive-decline
health1 year ago

"Brain Iron Levels Tied to Concussion Risk"

A study presented at the American Academy of Neurology's 76th Annual Meeting suggests that individuals with post-traumatic headaches following concussions may have higher levels of iron accumulation in specific brain regions, indicating cell injury. The research, supported by the U.S. Department of Defense and NIH, found that the extent of iron accumulation correlated with the number of concussions and frequency of headaches, potentially serving as a biomarker for concussion-related injuries and offering new insights into brain recovery processes.

via Neuroscience News|
#brain-injury#concussion#headaches
medical-research2 years ago

The Role of Iron Accumulation in Fibrosis and Senescence

Iron accumulation has been found to play a causative role in fibrogenesis, senescence, and the senescence-associated secretory phenotype (SASP). Fibrogenic injuries can lead to progressive iron accumulation in tissues, which promotes the secretion of pro-fibrotic cytokines, recruitment of immune cells, remodeling of the extracellular matrix, and activation of profibrogenic pathways. Iron accumulation also induces cellular senescence, characterized by the upregulation of senescence markers and DNA damage. These findings suggest that targeting iron accumulation may be a potential therapeutic strategy for fibrotic diseases.

via Nature.com|
#cellular-damage#fibrogenesis#fibrosis