Tag

Endometrial Cancer

All articles tagged with #endometrial cancer

Could ibuprofen lower some cancer risks? Early findings with caveats
health1 month ago

Could ibuprofen lower some cancer risks? Early findings with caveats

Emerging studies link regular ibuprofen use with lower risks of endometrial and bowel (colorectal) cancers, possibly by dampening inflammation and affecting cancer-related genes, though evidence is not conclusive and high-dose or long-term NSAID use can cause serious side effects. Experts caution against self-prescribing ibuprofen for cancer prevention and emphasize proven prevention strategies like a healthy weight, exercise, and a balanced diet.

Ibuprofen and Cancer Risk: Early Signals, Cautious Outlook
health1 month ago

Ibuprofen and Cancer Risk: Early Signals, Cautious Outlook

New research links ibuprofen’s anti-inflammatory action to possible cancer-risk modulation, including a potential lower risk of endometrial cancer and hints of protection against other cancers, but the evidence is mixed and experts warn against using ibuprofen for cancer prevention due to side effects and drug interactions; maintaining a healthy lifestyle remains the best prevention strategy.

Researchers Warn of New Reproductive Health Threats from Environmental and Biological Factors
health4 months ago

Researchers Warn of New Reproductive Health Threats from Environmental and Biological Factors

New research indicates that microplastic particles are present in all examined endometrial tissues and are significantly higher in cancerous tissues, potentially disrupting metabolic pathways and contributing to the development of endometrial cancer, raising concerns about the broader impact of plastic pollution on women's reproductive health.

Advancements in Urine-Based Testing and Treatments Show Promise for Bladder Cancer Survival
medical-research2 years ago

Advancements in Urine-Based Testing and Treatments Show Promise for Bladder Cancer Survival

A study published in BMC Women's Health utilized urine metabolomics to assess the efficacy of fertility-sparing treatment in endometrial cancer (EC) patients. The researchers analyzed urine samples using ultra-performance liquid chromatography mass spectrometry (UPLC-MS) and identified distinct metabolites and altered metabolic pathways. They developed a panel of biomarkers that demonstrated high predictive ability in identifying patients with complete remission (CR). The panel consisted of Baicalin, 5beta-1,3,7 (11)-Eudesmatrien-8-one, Indolylacryloylglycine, Edulitine, and Physapubenolide. This non-invasive approach offers a less invasive means of monitoring treatment efficacy and may aid in evaluating fertility-sparing treatments for EC patients. Further research is needed to validate the biomarker panel in larger populations.

GSK's Checkpoint Inhibitor and Chemotherapy Combo Improves Survival in Endometrial Cancer
healthcare2 years ago

GSK's Checkpoint Inhibitor and Chemotherapy Combo Improves Survival in Endometrial Cancer

GSK's checkpoint inhibitor, Jemperli, when added to chemotherapy, has been found to prolong the survival of patients with advanced or recurrent endometrial cancer in a Phase III study. The study met its primary overall survival endpoint, with patients receiving Jemperli-chemo treatment living longer than those in the comparator arm.

New drug combination shows promise in treating advanced endometrial cancer.
health2 years ago

New drug combination shows promise in treating advanced endometrial cancer.

Two studies published in the New England Journal of Medicine found that adding immunotherapy drug pembrolizumab to the standard chemotherapy regimen of carboplatin and paclitaxel reduced the risk that patients' advanced or recurrent endometrial cancer would return by up to 70%. The impact was more dramatic in women with a mismatch repair-deficient tumor, a specific type of endometrial cancer. The Food and Drug Administration would need to amend its guidance on using immunotherapy in this way before it's widely implemented as the protocol for treating late-stage endometrial cancer.