All articles tagged with #cholesterol metabolism
A new study suggests that increasing apolipoprotein M (ApoM) levels could slow or prevent age-related macular degeneration (AMD) by improving cholesterol processing in the retina, potentially offering a new treatment to preserve vision and benefit heart health, with promising results in mouse models.
A new study from WashU Medicine suggests that increasing levels of apolipoprotein M (ApoM) could prevent or slow age-related macular degeneration by fixing cholesterol processing issues, which are linked to both eye and heart diseases, offering a potential new treatment approach.
Newborn babies whose mothers used non-prescription opioids, particularly fentanyl, during pregnancy are displaying a range of birth defects, including small heads, short stature, and distinctive facial features. Doctors initially suspected a rare genetic condition, but genetic tests ruled it out. Further investigation suggests that prenatal exposure to fentanyl may be causing a previously unknown syndrome, possibly by disrupting cholesterol metabolism in fetuses. The exact mechanism is unclear, and it is uncertain whether the birth defects are directly caused by fentanyl or other substances. Researchers emphasize the importance of recognizing this condition due to the widespread use of fentanyl.
Researchers at Temple University's Lewis Katz School of Medicine are investigating the protein ABCA7 as a potential therapeutic target for Alzheimer's disease. A recent study published in Cells explored the relationship between ABCA7, cholesterol metabolism, and inflammation in human brain cells. The study found that cholesterol loss could downregulate ABCA7 in various brain cells, potentially contributing to the onset of Alzheimer's disease. Additionally, inflammation was found to suppress ABCA7 in certain brain cells. Further research is needed to fully understand the role of ABCA7 in Alzheimer's disease and develop targeted therapies.