All articles tagged with #cellular recycling
Scientists have discovered a new organelle called the hemifusome inside human cells, which plays a key role in cellular recycling and cargo management. This finding could provide new insights into genetic disorders like Hermansky-Pudlak syndrome and lead to novel treatments. The discovery was made using advanced cryo-electron tomography and opens new avenues for understanding cell health and disease.
A new study reveals how nutrient-starved cells repurpose protein transport stations to be directed to lysosomes for degradation, providing a novel insight into how cells cope with stressful conditions. The research demonstrates that under nutrient stress, a series of molecules work together to guide ER exit sites to lysosomes, where they are broken down to free up amino acids needed for protein synthesis inside the cell. This discovery sheds light on cellular stress responses and could have implications for understanding aging and developing new treatments for various processes involving ER exit sites.
Researchers at the University of Maryland School of Medicine have found that after traumatic brain injury (TBI), the brain's immune system cells' internal recycling function slows dramatically, allowing waste products to build up and interfere with recovery from injury. Treatment with rapamycin helps lower neuroinflammation and promotes cellular recycling following TBI. The study suggests that designing drugs for patients that promote cellular recycling might reverse or prevent damage from TBI.