All articles tagged with #body weight
A six-month study found that altering sugar intake does not change people's preference for sweetness, nor does it impact energy consumption or body weight, challenging the belief that eating sugar increases cravings or consumption.
The discussion around body weight has evolved with the body positivity movement and the classification of obesity as a disease, leading to changing attitudes and the development of powerful weight loss medications. However, weight stigma remains widespread, and the use of these medications is often accompanied by shame. The traditional method of categorizing weight using body mass index is flawed, and there's a growing understanding that different types of obesity may require different treatments. The arrival of effective new medications, such as semaglutide and tirzepatide, is seen as revolutionary, but societal attitudes toward weight and weight loss still need to evolve.
Glucose-dependent insulinotropic polypeptide (GIP) regulates body weight and food intake through GABAergic neurons, according to a study in mice. The study found that GIPR agonism is a vital component of GIPR-GLP-1R co-agonism, which has been effective in treating obesity and diabetes. Mice with Gipr deletion in inhibitory GABAergic neurons showed decreased body weight, improved glucose metabolism, and decreased food intake. The study also revealed that GIP acts on hindbrain GIPR neurons to regulate food intake, and GIP requires GIPR signaling in inhibitory GABAergic neurons to decrease food intake. These findings provide insights into the mechanisms underlying the metabolic effects of GIP and GIPR-GLP-1R co-agonism.
A study analyzing data from the Women's Health Initiative found that women who maintained a stable body weight over decades had higher odds of living to age 90 and beyond compared to those who lost weight. Women who unintentionally lost weight had significantly lower odds of survival. The study suggests that weight stability may be a predictor of longevity and cautions against blanket recommendations for weight loss in older women. Further research is needed to understand the connections between health problems, weight loss, and diverse racial and ethnic populations.
Eating a Mediterranean diet rich in vegetables, seafood, and whole grains appears to slow the signs of accelerated brain aging typically seen in obesity with as little as 1 percent loss in body weight. Brain scans taken after 18 months showed the participants' brain age appearing almost 9 months younger than expected, compared to estimates of their brain's chronological age. The study highlights the importance of a healthy lifestyle, including lower consumption of processed food, sweets, and beverages, in maintaining brain health.
A study by researchers from Université Laval and the Quebec Heart and Lung Institute Research Centre has identified 60 unique proteins expressed in the brain that may be critical regulators of body weight. The study explored the link between genetic regions associated with body weight and the proteins expressed in the brain. The team believes that the biological role of these proteins in various parts of the brain and their contribution to energy homeostasis needs to be studied in more detail. The evolving food environment may have influenced food behaviours and energy storage capacity over the last few decades.