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Beta Amyloid Plaques

All articles tagged with #beta amyloid plaques

health1 year ago•5 min saved

Innovative Nasal Spray Shows Promise in Delaying Alzheimer's Progression

Researchers at Texas A&M University have developed a nasal spray that, in mouse models, reduces neuroinflammation and beta-amyloid plaques associated with Alzheimer's disease, potentially delaying its progression by up to 15 years. The spray targets microglia and astrocytes, cells involved in brain inflammation, and has shown promising results in improving cognitive and mood functions in treated mice. While the findings are encouraging, experts emphasize the need for further research and human trials to confirm the spray's efficacy and safety.

via Medical News Today|

#alzheimers #beta-amyloid-plaques #cognitive-function

health1 year ago•6 min saved

"New Protein Target Offers Hope in Slowing Alzheimer's Progression"

Researchers from the Icahn School of Medicine at Mount Sinai have discovered that targeting the protein plexin-B1 in the brain may help clear beta-amyloid plaques, a hallmark of Alzheimer's disease. This early-stage research suggests that modifying cellular interactions involving plexin-B1 and reactive astrocytes could reduce neurotoxicity and neuroinflammation, potentially leading to new treatment options. However, experts caution that these findings are preliminary and need further validation in human studies.

via AOL|

#alzheimers-disease #beta-amyloid-plaques #health

health1 year ago•5 min saved

"New Protein Research and Plexin-B1 Offer Hope in Halting Alzheimer's Progression"

Researchers from the Icahn School of Medicine at Mount Sinai have discovered that targeting the protein plexin-B1 in reactive astrocytes can help clear beta-amyloid plaques, a hallmark of Alzheimer's disease. This finding could lead to new treatment options, although some experts remain skeptical about the focus on amyloid plaques. The study is still in early stages and was conducted on a genetic mouse model.

via Medical News Today|

#alzheimers-disease #beta-amyloid-plaques #health

health2 years ago•4 min saved

Resistance Training: A Powerful Defense Against Alzheimer's

Regular resistance exercise, such as weight training, can prevent or delay the onset of Alzheimer's disease symptoms, according to a study conducted on transgenic mice. The study found that resistance training reduced the formation of beta-amyloid plaques and normalized levels of corticosterone, a stress hormone linked to Alzheimer's. The anti-inflammatory effects of resistance training are believed to be a primary reason for its effectiveness in staving off Alzheimer's. The researchers concluded that resistance exercise could serve as an affordable and accessible therapy for Alzheimer's patients, with just four weeks of training shown to reverse behavioral and physical alterations associated with the disease.

via SciTechDaily|

#affordable-therapy #alzheimers-disease #beta-amyloid-plaques

health2 years ago•6 min saved

"Exploring the Potential of Vaccines in Preventing and Treating Alzheimer's Disease"

Researchers are exploring the use of vaccines as potential treatments for Alzheimer's disease. The current approach focuses on targeting beta-amyloid plaques, but drugs that remove these plaques have not shown significant impact on the disease. Some researchers propose that Alzheimer's may result from a poorly regulated immune response to infection, leading to inflammation and the overproduction of beta-amyloid. Vaccines could potentially retrain the immune system to fight the disease by stimulating the cells that clear beta-amyloid and suppressing the immune cascade responsible for its release. Vaccines such as Bacille Calmette-Guérin (BCG) and Protollin are being tested in clinical trials, while other companies are developing vaccines that directly target beta-amyloid. The safety and effectiveness of these vaccines are still being investigated, but they could potentially make Alzheimer's treatment more accessible and affordable compared to existing antibody therapies.

via Livescience.com|

#alzheimers-disease #beta-amyloid-plaques #health

health2 years ago•6 min saved

Harnessing the Power of Exercise to Combat Alzheimer's and Enhance Cognitive Performance

Resistance training, specifically the contraction of specific muscles against an external resistance, has been found to delay the onset of Alzheimer's disease and reduce Alzheimer's-associated behavioral issues, according to a study conducted on transgenic mice. The study demonstrated a decrease in the formation of beta-amyloid plaques, a key feature of Alzheimer's, and normalized stress hormone levels in mice that underwent resistance exercise training. The findings suggest that resistance training could serve as a cost-effective therapeutic option for Alzheimer's patients.

via Neuroscience News|

#alzheimers-disease #behavioral-issues #beta-amyloid-plaques