All articles tagged with #beige fat
Reducing two amino acids common in animal protein—methionine and cysteine—in mice boosted energy expenditure by about 20% via beige fat, causing weight loss without changing food intake or activity, and was comparable to constant cold exposure, suggesting diet alone could activate fat-burning pathways, though human relevance remains unproven and further work on safety and applicability is needed.
A mouse study shows beige fat around blood vessels helps keep blood pressure low by suppressing the enzyme QSOX1; when beige fat is converted to white fat, QSOX1 rises, leading to stiffer vessels and higher BP. Removing beige fat or blocking QSOX1 prevented hypertension in mice, suggesting beige fat has a local vascular role and that QSOX1 could be a target for future hypertension therapies.
Scientists at Cornell have discovered a way to potentially reverse age-related weight gain by reactivating beige fat, a type of fat that burns calories like brown fat. They identified a signaling pathway that suppresses beige fat formation with age and found that blocking this pathway, using existing cancer drugs, can restore fat-burning activity in older mice, offering promising avenues for combating metabolic decline and obesity-related diseases.
Stimulating the production of beige fat, a subtype of white adipose tissue, helps to reverse a slowing metabolism, which could prevent age-related weight gain and associated health disorders like Type 2 diabetes, heart disease, and chronic inflammation. The study shows therapeutic promise in beige fat, which has the same thermogenic properties as brown fat, reducing blood sugar and fatty acids that cause hardening of the arteries and heart disease. The researchers identified a specific signaling pathway that suppresses beige fat formation in older mice by antagonizing the immune system, which could be targeted to restore WAT immune cell function to stimulate beige fat in adult mammals.
Researchers at Cornell University have discovered that stimulating the production of beige fat cells could reverse the effects of a slowing metabolism, which could prevent age-related weight gain and associated health disorders like Type 2 diabetes, heart disease, and chronic inflammation. Beige fat has the same thermogenic properties as brown fat, which means it helps to reduce blood sugar and the fatty acids that cause hardening of the arteries and heart disease. The researchers identified a specific signaling pathway that suppresses beige fat formation in older mice by antagonizing the immune system, and by suppressing that pathway in aging mice, they were able to prompt beige fat production in aged animals that otherwise would not.