New research shows caffeine extends cell lifespan by activating the energy sensor AMPK, which helps cells repair DNA and manage stress, potentially contributing to increased longevity beyond just alertness benefits.
Scientists have discovered that caffeine activates an ancient enzyme called AMPK, which helps cells manage stress, repair damage, and potentially slow aging, revealing a new link between coffee consumption and long-term health.
A study from Queen Mary University of London reveals that caffeine may promote cellular longevity by activating the energy sensor AMPK, rather than directly affecting the growth regulator TOR, suggesting potential health and lifespan benefits from coffee consumption.
New research suggests caffeine may slow cellular aging by activating AMPK, an ancient energy-sensing pathway, which helps cells manage stress, repair DNA, and regulate growth, potentially contributing to health and longevity.
A study from Queen Mary University of London reveals that caffeine may slow cellular aging by activating the energy sensor AMPK, which influences cell growth, DNA repair, and stress response, potentially explaining some health benefits of caffeine related to aging and longevity.
Researchers at Kumamoto University have developed HPH-15, a new compound that outperforms metformin in managing Type 2 diabetes by effectively reducing blood glucose and fat accumulation. HPH-15 activates AMPK at lower doses, decreases subcutaneous fat, and has antifibrotic properties, offering a safer profile with reduced lactic acidosis risk. This breakthrough could revolutionize diabetes treatment by addressing both glucose control and obesity-related complications.
Maqui berries, native to Chile, are rich in polyphenols, particularly delphinidin, which have numerous health benefits. These include speeding up metabolism and fat burning, soothing dry and itchy eyes, lowering blood sugar and cholesterol levels, boosting immunity, improving brain function, reducing the risk of cancer, reversing skin aging, and improving gastrointestinal health. Maqui berry extract, containing high concentrations of bioavailable delphinidins, is recommended for optimal absorption and activation of AMPK, a master switch that controls energy and metabolism. Taking 500 mg of maqui extract daily is advised for overall reduction in oxidative stress and anti-aging effects.
Biologists at the University of California, Irvine have discovered that by eliminating the SAPS3 component of the AMPK protein complex, mice were able to maintain a normal energy balance even when consuming a high-fat diet. This finding reveals the potential for developing molecules that inhibit SAPS3 to help restore metabolic balance and combat metabolic disorders like obesity, diabetes, and fatty liver disease.