Ancient Gene Revives to Create Living Mouse from Pre-Animal Era

TL;DR Summary
Scientists have created a mouse using ancient genes from single-celled organisms, challenging previous beliefs about the evolution of stem cells. By introducing choanoflagellate genes into mouse cells, researchers generated induced pluripotent stem cells, which contributed to the development of a chimera mouse. This discovery suggests that key genes involved in stem cell formation may have originated long before multicellular life, offering new insights for regenerative medicine.
- “Extraordinary” Mouse Created Using Gene That’s Older Than Animal Life Itself IFLScience
- Ancient Gene Reprograms Stem Cells to Create a Living Mouse Neuroscience News
- The origin of stem cells mpg.de
- Researchers Recreate Mouse from Choanoflagellate Gene that Predates Animals Sci.News
- The emergence of Sox and POU transcription factors predates the origins of animal stem cells Nature.com
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