Exercise Activates Brain Cells to Combat Alzheimer’s
TL;DR Summary
Researchers used advanced RNA sequencing to map how exercise impacts specific brain cell types in a model of Alzheimer’s disease, finding that physical activity alters gene activity in microglia and neurovascular astrocytes, promotes neuron formation via the gene Atpif1, and these findings were validated in human brain tissue, offering new avenues for targeted Alzheimer’s therapies.
- Exercise Rewires Alzheimer’s-Affected Brain Cells Neuroscience News
- Protective exercise responses in the dentate gyrus of Alzheimer’s disease mouse model revealed with single-nucleus RNA-sequencing Nature
- How physical activity protects the brain—cell by cell—in Alzheimer's disease Medical Xpress
- Movement Mobilizes Microglia, Astrocytes to Protect Against Alzheimer's in snRNA-seq Mice Study Genetic Engineering and Biotechnology News
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