The Evolutionary Mystery of Human Tail Loss Unraveled

After 2.5 years, researchers have identified a genetic change shared by humans and other apes that might have contributed to their ancestors’ tail loss some 25 million years ago. The study involved developing several strains of gene-edited mice to demonstrate the genetic changes' effects, leading to the publication delay. The findings suggest that a DNA insertion in the TBXT gene can lead to shortened or absent tails in mice, shedding light on the genetic mechanisms behind tail loss and length reduction in apes, although it's not the only factor involved. This research provides insight into the evolution of tail loss and its potential impact on apes' ability to walk upright.