MIT's Revolutionary Gene Regulation Visualization Breakthrough

MIT researchers have developed a new technique called Region Capture Micro-C (RCMC) for mapping the 3D structure of the human genome with 100 times higher resolution than before, enabling them to observe previously unseen interactions between enhancers and promoters. This technique allows scientists to focus on specific genome segments of interest and could help researchers understand how genetic diseases arise and potentially develop new treatments. The researchers’ findings suggest that many genes interact with dozens of different regulatory elements, although further study is needed to determine which of those interactions are the most important to the regulation of a given gene.