Uncovering the Molecular Mechanisms of Mammalian Hibernation

A study published in eLife has revealed new insights into the molecular mechanisms underlying hibernation in mammals. The research suggests that myosin, a motor protein involved in muscle contraction, plays a role in non-shivering thermogenesis during hibernation. The study found that changes in the proportion of myosin in different resting states may contribute to reduced energy use during hibernation. The findings also indicate that small hibernating mammals experience increased ATP consumption during torpor, potentially as a response to cold exposure. Additionally, the study highlights the importance of further research into muscle samples from different areas of hibernating animals to validate these findings.