Workout-Driven Shield: How Exercise Tightens the Brain’s Barrier to Preserve Memory

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Source: SciTechDaily
Workout-Driven Shield: How Exercise Tightens the Brain’s Barrier to Preserve Memory
Photo: SciTechDaily
TL;DR Summary

UC San Francisco researchers show that exercise increases the liver enzyme GPLD1, which travels to brain blood vessels and removes TNAP from the blood-brain barrier. This restores barrier integrity and reduces leakiness and inflammation in aging mice, helping memory and cognitive performance, and suggesting new therapeutic avenues for aging and Alzheimer’s-related decline.

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