Tracking Protein Shifts in the Aging Process

Researchers at Osaka Metropolitan University have developed the Mouse Aging Proteomic Atlas, a comprehensive database mapping protein changes in major tissues of aging mice. This atlas reveals proteins linked to aging, particularly in the extracellular matrix, enhancing our understanding of molecular aging and identifying potential targets for preventing age-related diseases. The study provides valuable insights into age-related post-transcriptional dysregulation and its impact on protein expression across different tissues.