Synergy of Electrical and Calcium Signals Enhances Brain Performance

Researchers at the University of Vermont have discovered a mechanism called Electro-Calcium (E-Ca) coupling, which integrates electrical and calcium signaling in brain capillaries to regulate blood flow to active neurons. This process enhances blood flow by 76%, offering potential therapeutic insights for neurological diseases like Alzheimer's by restoring disrupted blood flow. The study highlights the interconnected role of electrical and calcium signals in maintaining brain health and cognitive function.