Psychedelics Remodel Brain Myelin for Lasting PTSD Recovery

TL;DR Summary
A rat study shows psilocybin and MDMA trigger adaptive myelination, repairing the brain’s insulation (myelin) in fear circuits and producing long-lasting reductions in anxiety-like behavior; blocking myelin repair abolishes the benefits, indicating myelin remodeling is a key mechanism for durable psychedelic-assisted PTSD therapy and should complement, not replace, psychotherapy.
- Psychedelics Remodel Myelin to Heal PTSD Neuroscience News
- Psychedelics may aid PTSD recovery by repairing brain myelin, study finds Medical Xpress
- MDMA and Psilocybin Regulate Oligodendrocyte-Lineage Cell Numbers and Anxiety-Like Behaviors in a Rat Model of Fear EurekAlert!
- Scientists Find Missing Link to Psychedelics Like MDMA ‘Locking In’ PTSD Recovery Benefits The Debrief
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