Dietary methionine may steer disease outcomes by boosting kidney clearance and reducing inflammation

Salk Institute researchers found that methionine supplementation in infected mice boosted kidney filtration, lowered circulating cytokines, and improved blood flow, shifting disease trajectories away from inflammation-related damage toward recovery—protecting against wasting, blood-brain barrier disruption, sepsis, and death. The effect did not impair immune response, but human efficacy remains untested and further studies are needed to translate this to clinical use, including for kidney disease or dialysis patients.