Decoding Memory: Molecular Signals in the Hippocampus

A study by ISTA and the Max Planck Institute reveals molecular mechanisms of memory formation in the hippocampus, focusing on mossy fiber synapses. Researchers found that proteins Cav2.1 and Munc13 rearrange during memory processing, enhancing synapse precision and power. Using live mouse brain tissue and advanced imaging, the study provides real-time insights into how neurotransmitters and synaptic plasticity enable the hippocampus to encode experiences, offering a foundation for understanding memory-related disorders.