Brain Circuit Identified as Key to Turning Off Chronic Pain

TL;DR Summary
Scientists have identified a specific brainstem circuit involving Y1 receptor neurons in the parabrachial nucleus that can switch off chronic pain, revealing potential new avenues for treatment and understanding how the brain prioritizes survival needs over pain signals.
- Scientists discover brain circuit that can switch off chronic pain ScienceDaily
- A built-in ‘off switch’ to stop persistent pain Penn Today
- A parabrachial hub for need-state control of enduring pain Nature
- Parabrachial Nucleus Identified as Key Brainstem Hub in Chronic Pain Processing geneonline.com
- Hunger, Fear, and the Brain’s Hidden Switch to Turn Off Chronic Pain Neuroscience News
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