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Aging brain's slow protein recycling may fuel synapse decline tied to Alzheimer's

1 min read
Source: ScienceAlert
Aging brain's slow protein recycling may fuel synapse decline tied to Alzheimer's
Photo: ScienceAlert
TL;DR Summary

Age-related slowdown of neuronal protein recycling leads to protein clumps at synapses; microglia attempt cleanup but can become overwhelmed, potentially impairing neuron communication and linking aging to synaptic loss and higher neurodegenerative risk, with new targets for therapy and biomarkers suggested.

Topics:health#aging#alzheimers-disease#microglia#protein-turnover#science#synapses
Share this article
  1. A Hidden Brain Process May Help Explain Why Alzheimer's Risk Rises With Age  ScienceAlert
  2. Scientists Uncover Key Aging Protein That May Trigger Neurodegenerative Disease  SciTechDaily
  3. New cellular discovery may explain how Alzheimer’s disease spreads through the brain  AOL.com

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