"Genetic Risk Tracking Tool for CRISPR Edits Unveiled"

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Source: Phys.org
"Genetic Risk Tracking Tool for CRISPR Edits Unveiled"
Photo: Phys.org
TL;DR Summary

Researchers at the University of California San Diego have developed a new genetic analysis tool, the Integrated Classifier Pipeline (ICP), to track on- and off-target mutational edits resulting from CRISPR-based DNA repair outcomes. The ICP system can reveal specific categories of potentially risky mutations and help untangle complex biological issues related to CRISPR editing. This tool has the potential for various applications in human health, including gene therapy and tumor progression analysis, as well as tracking inheritance across generations in gene drive systems.

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