Boosting NAD+ Rewires RNA Splicing to Undo Alzheimer's Brain Damage
TL;DR Summary
An international study shows boosting NAD+ levels can protect and reverse Alzheimer's-related brain damage by activating an EVA1C-regulated RNA-splicing pathway, correcting mis-splicing, improving hundreds of genes tied to brain health, and restoring memory in worm and mouse models with supporting human brain data—hinting at a new therapeutic approach beyond targeting plaques or tangles.
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