Amygdala's Involvement in Seizure-Related Breathing Failure Revealed

Researchers have identified a potential brain mechanism associated with sudden unexpected death in epilepsy (SUDEP). By studying individuals with uncontrollable epilepsy, they found a correlation between the amygdala, a brain region involved in emotion processing, and postictal apnea, a dangerous pause in breathing after a seizure. Seizures originating in specific amygdala subregions may suppress breathing and the alarm signal of "air hunger," potentially through novel connections to the brainstem. These findings provide insights into SUDEP and open avenues for further research, preventive measures, and targeted treatments.