"Discovery of Rare Gene Mutation Halves Parkinson's Disease Risk"

Researchers have discovered a rare genetic mutation in a small protein, SHLP2, that halves the risk of developing Parkinson's disease, primarily found in people of European descent. This mutation is associated with better protection against mitochondrial dysfunction, a key factor in the disease. The discovery could lead to new treatments for Parkinson's and sheds light on the potential of exploring mitochondrial-derived microproteins for preventing and treating age-related diseases.