Unraveling the Genetic Origins of Multiple Sclerosis through Ancient DNA

Scientists have created the largest ancient DNA database, revealing that genetic variants which once protected prehistoric populations from pathogens may now increase the risk of diseases like multiple sclerosis and Alzheimer's in Europeans. The research, published in Nature, shows how the genetic roots of diseases and traits have evolved over time as populations migrated and interbred. The findings provide new insights into the genetic origins of multiple sclerosis and Alzheimer's, shedding light on how ancient lifestyles impact modern disease risk.