All articles tagged with #weight regulation
Researchers have discovered a novel compound, BHB-Phe, which regulates appetite and body weight by interacting with neurons in the brain. Produced by the enzyme CNDP2, BHB-Phe influences feeding behavior and metabolism, as shown in animal models. The study suggests that BHB-Phe could potentially be used to drive weight loss without dietary restrictions, opening new avenues for obesity treatment.
Researchers at the University of Aberdeen Rowett Institute have discovered a cluster of brain cells that control food intake and body weight by dampening hunger signals using the chemical GABA. This finding could lead to the development of targeted obesity medication that reduces food intake without causing nausea, offering new strategies for weight regulation.
Researchers have discovered that astrocytes, star-shaped cells in the brain, regulate fat metabolism and obesity by acting on a cluster of neurons called the GABRA5 cluster. A new drug called KDS2010, which inhibits the MAO-B enzyme in astrocytes, has shown promising results in facilitating weight loss in obese mice without reducing food intake, even on a high-fat diet. This breakthrough could lead to a new obesity treatment that allows individuals to lose weight without compromising appetite or avoiding fats. The drug is currently in Phase 1 clinical trials.