Scientists in Japan have developed a drug that can potentially regrow human teeth by suppressing the USAG-1 antibody, with successful trials on mice and plans for human trials, aiming for availability by 2030.
A tooth-growing drug that stimulates tooth regeneration is set to enter clinical trials in July 2024. The drug targets tooth agenesis, a genetic condition causing the absence of teeth, and aims to enable tooth regrowth. Researchers discovered that blocking the interaction of the uterine sensitization-associated gene-1 (USAG-1) with other genes stimulates tooth growth in mice. If successful, this drug could revolutionize dental treatments and provide a solution for tooth loss and lack of tooth growth in humans. The goal is to make the treatment widely available by 2030.