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Til Therapy

All articles tagged with #til therapy

"FDA Grants Accelerated Approval to Iovance's AMTAGVI™ for Advanced Melanoma Treatment"
health-medicine1 year ago

"FDA Grants Accelerated Approval to Iovance's AMTAGVI™ for Advanced Melanoma Treatment"

The FDA has approved a groundbreaking cancer therapy called Amtagvi, developed by Iovance Biotherapeutics, for metastatic melanoma patients. The treatment, known as TIL therapy, involves boosting immune cells inside tumors to fight cancer and is the first cellular therapy approved for solid tumors. While the approval is currently for melanoma, experts believe it holds promise for treating other solid tumors. TIL therapy has shown promising results in shrinking tumors and achieving complete remissions in some patients, offering hope for those with limited treatment options.

Revitalizing Exhausted Immune Cells to Eliminate Late-Stage Tumors
health2 years ago

Revitalizing Exhausted Immune Cells to Eliminate Late-Stage Tumors

Scientists at Cardiff University have discovered a type of T-cell in the blood of a late-stage cancer survivor that may be highly effective at recognizing and attacking tumors. These "multi-pronged" T-cells have the potential to respond to various types of cancer, not just melanoma. The researchers hope to investigate whether engineered multi-pronged T-cells can be used to treat a wide range of cancers, similar to how CAR-T cells are used to treat certain types of leukemia. TIL therapy, which involves enhancing a patient's own T-cells to better attack cancer, has shown promising results in clinical trials, but the cellular mechanisms behind its success are still not fully understood.

Biotech discovers solid tumor-killing immune cells in patients' blood.
biotech2 years ago

Biotech discovers solid tumor-killing immune cells in patients' blood.

Chicago-based CTRL Therapeutics has raised $10m to develop a new autologous cell therapy that aims to expand beyond the current scope of cancers treated by existing cell therapies and introduce a less complex process for patients and manufacturers. The company is building on another next-generation cell therapy method known as tumor infiltrating lymphocyte, or TIL, therapy, which requires surgically removing cells from the patient’s tumor.