The Vatican's rejection of changing biological sex is a setback for transgender individuals, reflecting diverse approaches to gender identity in major religions. While some denominations disapprove of gender transition, others, like the Evangelical Lutheran Church in America, welcome trans people. In Islam, policies on sex conversion vary, with Iran officially supporting gender transition surgery. Hinduism recognizes third gender people, but they face marginalization and lack access to resources. Buddhism's views on gender roles differ across traditions, with some being more inclusive of transgender individuals. Reform Judaism accepts transgender people, while Orthodox Judaism presents challenges for them due to its emphasis on binary gender roles.