Tag

Protein Biomarkers

All articles tagged with #protein biomarkers

"Breakthrough Blood Test Predicts Alzheimer's Decades in Advance"
health-research1 year ago

"Breakthrough Blood Test Predicts Alzheimer's Decades in Advance"

A study has identified 11 blood proteins that can predict dementia with 90% accuracy up to 15 years before clinical diagnosis. These proteins, including GFAP, NEFL, GDF15, and LTBP2, act as warning signs for the disease and could revolutionize dementia diagnosis by providing early support and access to treatment. The findings suggest that blood tests could replace invasive and costly diagnostic methods, potentially improving the quality of life for dementia patients.

Alnylam's RNAi approach shows sustained benefits in Alzheimer's patients
health2 years ago

Alnylam's RNAi approach shows sustained benefits in Alzheimer's patients

Alnylam's experimental drug for Alzheimer's disease has shown promising benefits in patients for up to six months. The drug, which utilizes RNA interference to silence disease-causing genes, resulted in significant reductions in protein biomarkers associated with the formation of amyloid plaques in the brain. The levels of these biomarkers remained 55 to 65 percent lower than before treatment six months after receiving the drug. The results suggest the potential for administering two doses per year to maintain reduced protein levels. Alnylam's drug is the first to target a gene causing a brain disease, serving as a proof of concept for RNA interference drugs in neurodegenerative disorders. Further studies are needed to determine if reducing protein biomarkers slows the progression of Alzheimer's.