
Stem-cell derived 'pain sponge' targets pain at the source in arthritis
Researchers engineered human pluripotent stem cell–derived sensory neurons that act as a biological "pain sponge," soaking up inflammatory pain signals at the site of inflammation in mice with osteoarthritis and also promoting bone and cartilage repair. The SN101 approach is in preclinical stages, with safety, immune response and translation to humans unresolved and no peer‑reviewed human data yet.

