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Polyphosphate

All articles tagged with #polyphosphate

Safe and Effective Drug Prevents Blood Clots without Bleeding Risk

Originally Published 2 years ago — by Study Finds

Canadian researchers have developed a new compound called MPI 8 that can prevent blood clots without increasing the risk of bleeding, a common side-effect of existing blood thinners. The compound targets polyphosphate, a molecule involved in blood clotting, and leaves the body's other cells and proteins alone, eliminating any toxic side-effects. Animal studies have shown that MPI 8 is effective in preventing blood clots in mice without increasing bleeding risk and has no toxic side-effects, even at high doses. However, more research is necessary to test the safety and effectiveness of MPI 8 in humans.

health health blood-clots blood-thinners health mpi-8 polyphosphate research

New blood thinner reduces risk of bleeding.

Originally Published 2 years ago — by Medical News Today

Researchers at the University of British Columbia and the University of Michigan have developed a new compound, MPI 8, that targets just one clotting pathway to prevent thrombosis, without increasing the risk of bleeding or toxicity. Anticoagulants, or blood thinners, can prevent clotting altogether, resulting in excessive external or internal bleeding. MPI 8 targets polyphosphate, a molecule involved in blood clotting, and has been found effective at preventing blood clots without toxicity or an increase in the risk of bleeding in mice. The researchers hope to move next to trials with larger animals and eventually humans.

health health anticoagulants bleeding-risk blood-clots health mpi-8 polyphosphate