All articles tagged with #non opioid
A Texas hospital, UT Health San Antonio, is pioneering the use of suzetrigine, a newly approved non-opioid painkiller, for post-surgical pain management, aiming to reduce reliance on narcotics and their side effects by using innovative, multimodal pain control strategies.
A new non-opioid painkiller called ADRIANA, developed in Japan, shows promising early clinical trial results and could provide a safer alternative for severe pain management, potentially helping to reduce the global opioid crisis.
Tonix Pharmaceuticals' drug Tonmya has received FDA approval for treating fibromyalgia in adults, marking the first new therapy in over 15 years for this condition. The medication, a non-opioid, once-daily sublingual tablet, demonstrated significant pain reduction in clinical trials and is expected to be available in the US by late 2025.
Tonix Pharmaceuticals received FDA approval for Tonmya™, a non-opioid, sublingual tablet for fibromyalgia in adults, marking the first new treatment in over 15 years. The drug demonstrated significant pain reduction in Phase 3 trials and is expected to launch in Q4 2025, targeting over 10 million affected U.S. adults.
Vertex Pharmaceuticals has developed an experimental drug, VX-548, that targets moderate to severe acute pain by blocking pain signals at the source, potentially avoiding the risk of addiction associated with opioids. The company reported positive results from two randomized studies and plans to seek FDA approval for the drug by midyear. If approved, this non-opioid medication could offer a new approach to pain relief, with potential implications for addressing the opioid addiction crisis.
Vertex Pharmaceuticals' experimental non-opioid drug, VX-548, has shown promising results in two Phase III studies, with over 1,000 participants each, by significantly reducing post-surgery pain levels compared to a placebo. The drug's success marks a potential breakthrough in the search for non-addictive pain medication.
Researchers have discovered a non-opioid pathway in the brain that provides pain relief similar to opioids but without the risk of addiction. By targeting the acetylcholine receptor alpha-7 (⍺7) in the ventrolateral periaqueductal gray (vlPAG) region of the brain, the team observed a lasting analgesic effect in mice, even those tolerant to opioids. This finding opens up new possibilities for the development of non-opioid pain medications, potentially revolutionizing pain treatment.