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Mitochondrial Disorders

All articles tagged with #mitochondrial disorders

science-and-technology1 year ago•3 min saved

Mini-Brains Unlock Secrets of Mitochondrial Disorders

Researchers at the University of Bergen have developed mini-brains, or brain organoids, to study mitochondrial dysfunction in brain cells, offering new insights into treating conditions like epilepsy, Alzheimer's, and Parkinson's diseases. These organoids mimic disease processes, allowing for real-time observation and testing of potential treatments, potentially revolutionizing the understanding and treatment of mitochondrial brain disorders.

via Neuroscience News|

#alzheimers-disease #brain-organoids #epilepsy

health2 years ago•3 min saved

Mitochondrial Disorders Linked to Weaker Immune Response in Children

Researchers at the National Human Genome Research Institute (NHGRI) have found that children with mitochondrial disorders have a weaker and less diverse antibody response to viral infections due to altered B cell function. The study, one of the first to examine how B cells are affected in mitochondrial disease, analyzed gene activities of immune cells and discovered that B cells are less able to survive cellular stress. This weakened immune response puts children with mitochondrial disorders at a higher risk of life-threatening infections. The findings aim to guide future treatments for patients with mitochondrial disorders.

via National Institutes of Health (.gov)|

#b-cells #genetic-diseases #health