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Methylenomycin

All articles tagged with #methylenomycin

health2 months ago

New Antibiotic from Streptomyces Coelicolor Shows Promise Against Resistant Bacteria

Researchers discovered a new, potent antibiotic intermediate called pre-methylenomycin C lactone in the bacterium Streptomyces coelicolor, which is over 100 times more effective against resistant Gram-positive bacteria like MRSA and VRE, with no detected resistance development, offering promising potential in combating antimicrobial resistance.

science2 months ago

Chemists Find Hidden Antibiotic for Drug-Resistant Bacteria

Chemists from Warwick and Monash Universities discovered a new, potent antibiotic, pre-methylenomycin C lactone, hiding as an intermediate in the natural biosynthesis of methylenomycin A. This compound shows over 100 times greater activity against Gram-positive bacteria, including resistant strains like MRSA and VRE, and may offer a new approach to combat antimicrobial resistance. The next steps involve pre-clinical testing and further development.