
"Unraveling the Dual Mechanisms of Aging: Drivers vs. Passengers"
Researchers are exploring the distinction between driver and passenger mechanisms of aging, examining factors such as DNA damage, telomeres, and cellular senescence. Studies have delved into the role of oxidative damage, mitochondrial function, and somatic mutations in the aging process, while also investigating the impact of telomere length and cellular senescence on lifespan. The identification of p16Ink4a-positive cells and the vulnerability of somatic progenitor cells to mitochondrial DNA mutagenesis have also been highlighted as potential contributors to aging.

