All articles tagged with #ketone bodies
Fasting triggers the production of ketone bodies like β‑hydroxybutyrate, which can bind to misfolded proteins in the brain, promoting their removal and potentially improving brain health and memory, with promising results in animal studies and early human trials.
Research from the Buck Institute reveals that ketone bodies, particularly β-hydroxybutyrate, can aid in clearing damaged proteins in the brain by altering their solubility and promoting autophagy. This discovery, tested in mouse models of Alzheimer's and aging, suggests a new metabolic link to neurodegeneration and aging, offering potential therapeutic pathways. The study highlights ketone bodies as signaling metabolites that improve brain health beyond their energy-providing role during fasting.