
Revolutionary Treatment Approach Unveiled for Osteoarthritis and Neurodegenerative Diseases
Researchers have discovered that elevated levels of the protein c-Fos are associated with the severity of osteoarthritis, a common degenerative joint disease affecting over 500 million people worldwide. This breakthrough provides new insights into potential targeted therapies and challenges the previous belief that osteoarthritis solely stems from wear and tear. The study, led by scientists at MedUni Vienna, found that c-Fos is secreted by cartilage cells in response to osteoarthritis signals and plays a role in protecting cartilage. The research team also deciphered the mechanism controlling the production and accumulation of c-Fos in cartilage cells, paving the way for the development of targeted therapies.
