All articles tagged with #intranasal vaccine
Stanford Medicine researchers report an intranasal vaccine that activates innate and adaptive immunity to provide months-long protection in mice against a broad spectrum of respiratory threats—SARS-CoV-2 and other coronaviruses, Staphylococcus aureus, Acinetobacter baumannii, and house dust mite allergen—suggesting a path toward a universal respiratory vaccine, with human safety trials planned next.
A phase I study presented at the IDWeek meeting showed that an intranasal COVID-19 vaccine candidate, CoviLiv, produced a strong immune response in healthy adults, with participants exhibiting increased levels of spike-specific antibodies and interferon-gamma response. The vaccine does not require cold chain storage and could potentially increase access to vaccinations in underserved areas. Additionally, researchers discussed the use of wastewater surveillance as a tool to predict outbreaks of respiratory viruses such as influenza and respiratory syncytial virus (RSV). Lastly, a maternal RSV vaccine was highlighted as a potential strategy to reduce hospitalizations and costs associated with RSV infection in infants.