Tag

Immune Genes

All articles tagged with #immune genes

science2 years ago

"The Black Death's Impact on Human Genetic History: A New Study's Findings"

A recent study challenges the claim that the Black Death had a lasting impact on the genomes of the people of Cambridge, England. While a high-profile 2022 study suggested that variants in immune genes enriched in survivors might have had a protective effect, the latest research found little evidence supporting adaptation of immune responses. The debate over the Black Death's impact on human genomes continues, with researchers emphasizing the need for larger sample sizes and more comprehensive studies to reach definitive conclusions.

health2 years ago

The Hidden Link Between Brain Barrier Inflammation and Multiple Sclerosis

Inflammation in the brain's barrier, known as the meninges, may contribute to the progression of multiple sclerosis (MS), according to a study in mice. Using spatial transcriptomics, researchers found evidence of immune genes and inflammatory markers transitioning from the meninges into the adjacent brain tissue. This inflammation within the meninges, present in all types of MS, is suggested to play a role in nerve demyelination, loss of new neurites, and decrease in grey matter volume. The study provides valuable insights into the mechanisms of brain damage in MS and highlights the need for further research using human samples.